When not using hardware handshaking, space messages sufficiently apart. The host must not communicate with the scanner if the scanner is transmitting.
When using hardware handshaking, frame each message properly with handshaking signals. Do not try to send two commands within the same handshaking frame.
There is a permanent/temporary bit in the PARAM_SEND message. Removing power from the scanner discards temporary changes. Permanent changes are written to non-volatile memory. Frequent changes shorten the life of the non-volatile memory.